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• THYROID CANCER ANATOMY
• Thyroid cancer epidemiology
• Pathology
• Follicular cell origin (FCDC)
• Parafollicular (C cells) – medullary
• FCDC
• Papillary (and follicular variant – FVPTC) (most)
• Follicular
• Oxyphilic (Hurthle cell)
• Anaplastic
• Diagnosis
• History/examination (MEN, MTC FH)
• TNM staging system
• Ultrasound-guided FNAB of clinical or radiologically detected mass
• Thyroid and Neck ultrasound
• Serum Ca 2+
• CT scan neck/superior mediastinum/chest
• ENT exam (vocal cords)
• Well Differentiated Thyroid Carcinoma PTC
• INDICATIONS FOR EBRT RADICAL RT
• MEDULLARY CARCINOMA

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Lecture outline:
Classification & Incidence of Thyroid Cancer:

Follicular cell origin
Differentiated
Papillary 80%
Follicular 10%
Hurthle cell 3-5%
Undifferentiated
Anaplastic 1-2%
Parafollicular cell origin
– Medullary 5%
Medullary Thyroid Carcinoma
MEN IIA 
Lymphoma of the Thyroid

Evaluating a thyroid nodule
Which of the following are concerning findings on ultrasound?
Prognostic Risk Classification for Patients with Well-Differentiated Thyroid Cancer (AMES or AGES)

Clinical cases